I harp on this from time to time, but I still hear (and deal with) the negative ramifications from a failure to back up the little stuff. It can be nearly as catastrophic as failing to back up the big stuff. Every IT shop should have had backups hammered into their heads long ago and should be performing GFS-or-better backups for all the servers and the data. If they're virtual servers, you're backing up the images: databases, apps, terminal servers, all of it. But I'd be willing to wager that a significant number of these shops hit all the big stuff but miss the little stuff.
So let's define little stuff. In no particular order, they are router, switch, and firewall configurations; firmware images for those devices; and BIOS and controller images for servers, blade chassis, and whatnot. These are the things that you rarely, if ever, need, but when you do, you need them more than anything else in the entire infrastructure. The hardware failure rate for routers and switches is perhaps less than servers, but hardware failure is by no means the only reason to suddenly need a backup of a router configuration file.
There are a few free/open source ways to automate these backups, preferably to a server that itself is backed up. One of my favorites is the now somewhat abandoned Pancho. Although the latest release is four years old, it works on hardened fundamentals (SNMP and telnet) to pull full configurations via TFTP from a myriad of different routers and switches on a scheduled basis. The configuration file syntax is extremely simple and basically boils down to:
Voila. With Pancho run as a cron job, those routers and switches will now have their configurations archived in perpetuity.